Inhibition of HMC-1 Mast Cell Proliferation by Vitamin E

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Inhibition of HMC-1 mast cell proliferation by vitamin E: involvement of the protein kinase B pathway.

The effects of four natural tocopherols on the proliferation and signaling pathways were examined in the human mastocytoma cell line (HMC-1). The four tocopherols inhibited HMC-1 cell proliferation with different potency (delta > alpha = gamma > beta). Growth inhibition correlated with the reduction of PKB (protein kinase B) phosphorylation by the different tocopherols. The reduction of PKB pho...

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Swiprosin-1 Regulates Cytokine Expression of Human Mast Cell Line HMC-1 through Actin Remodeling

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Functional Expression of TRPV4 Cation Channels in Human Mast Cell Line (HMC-1).

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ژورنال

عنوان ژورنال: Journal of Biological Chemistry

سال: 2004

ISSN: 0021-9258

DOI: 10.1074/jbc.m410800200